Epigenetic Modifications

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  • Vikas Kumar

    Apr 10th, 2022

Targeting a gene for epigenetic modification by a transcription factor. In some cases, transcription factors may bind to a specific gene and initiate a series of events that leads to an epigenetic modification. For example, particular transcription factors in stem cells initiate epigenetic modifications that cause the cells to follow a specific pathway of development. For this to occur, the transcription factors recognize specific sites in the genome and recruit proteins to those sites, such as histone-modifying enzymes and DNA methyltransferase. This recruitment leads to epigenetic changes, such as changes in chromatin structure and DNA methylation. Please go through the diagram for the illustration.

Author

Vikas Kumar

Vikas Kumar

Dr. Vikas did Masters, M. Phil. & Ph.D. from Delhi University. He was one of the gold medalists in the university during Masters in Zoology. He has published many research papers in drug designing & development. He is Assistant Professor in the University of Delhi. He believes in educating and not just teaching his students and enable them by inculcating scientific temperament to solve challenges in the field of Animal sciences.